Bulletin N° 04/2008 : Cancer localisé de la prostate : traitement par radiothérapie exclusive guidée par l’imagerie, expérience au Luxembourg en 2005 et 2006 M.Untereiner, S.Renard-Oldrini, H.Mecellem, D.Burie, Y.Lassen, R.Ruchaud Phy, S.Joseph Phy, L.Harzee Phy
	Exclusive radiotherapy is one of therapeutic standard in the curative treatment of localized prostate cancer. Results are equivalent when compared with other treatment regimens (radical prostatectomy or curietherapy) in localized forms. However,the patients risks profiles to predict noxious effects are different. Between 2005 and 2006, 27 patients have been treated with intensity modulated radiation therapy and image-guided radiotherapy (IGRT), after implantation of gold markers to target prostate localization during daily radiotherapy seances. The total dose of radiation delivered in prostate is 74 Gy with respect to the maximal dose defined to the rectum and to the bladder. Late toxicity was limited to grade 2(rectitis and cystitis). These symptoms were temporary. One patient out of 20 patients with one-year follow-up experienced biological recurrence with metastasis progression. New radiotherapy technologies have allowed to reduce the incidence of the toxicity especially late rectal toxicity (2.2 % in 2006) within a limited time period (one-year minimum). Telécharger l'article complet
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